Memorial Sloan Kettering Cancer Center
“Nattokinase supports clot prevention and helps improve overall blood circulation.”
Rated 4.7 Excellent | 12,220 Reviews
The clinically dosed nattokinase your circulation actually needs
Three small, odourless, enteric-coated capsules each morning deliver a full 10,800 FU of nattokinase with K2 and rutin, to warm cold hands and feet, support healthy blood pressure and lipids, and keep
0%
Noticed warmer hands and feetwithin the first few weeks of daily use0%
Said their legs felt lighter by eveningeven after long days sitting or standing0%
Felt reassured about their artery healthknowing they were taking a real clinical dose0%
Would recommend Natto to a friendover other nattokinase supplements they've tried30 Day Money-Back Guarantee
Clinically Studied.Warmer Hands. Healthier Arteries.
When a real clinical-strength enzyme dose meets enteric delivery, your circulation finally feels it.
Refill for less thanks to CycleSeal™
Your Natto bottle isn't just a bottle. It's a matte white ceramic vault built to keep every dose of your circulation stack as strong as day one, refill after refill.
- Airtight and light-blocked
- CycleSeal™ keeps every dose in an airtight, zero-light container, ensuring long-lasting full effectiveness per dose.
- Up to 54% off every cycle
- Thanks to our proprietary CycleSeal™ technology, you get up to 54% off every refill cycle, permanently, with the freedom to pause or cancel anytime.
- Cheaper and less wasteful
- With CycleSeal™, you keep the durable container and replace only the lighter refill pouch, cutting packaging waste while keeping every cycle cheaper.
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12 Clinically-Dosed Circulation Actives For Warmer Hands, Clearer Arteries, Steadier Numbers
Twelve actives, every one dosed at a level that actually does something, working from your extremities to your artery walls.
Nattokinase
The clinical-strength dose the category skips. This fermentation-derived enzyme is the fibrin-clearing engine of the formula, delivered enteric-coated so it survives your stomach and reaches your bloodstream intact.
Vitamin K2 (as menaquinone-7)
Steers calcium away from your arteries. This all-trans MK-7 form works alongside the enzyme on your lipid profile while directing calcium toward bone instead of arterial walls.
Rutin
Reinforces the vessel walls carrying that fresh blood flow. This bioflavonoid strengthens capillaries and vein walls so circulation improves without vessels losing structural integrity.
Micronized Diosmin
Targets the heavy, tired feeling in your legs. This micronized flavonoid is dosed for genuine venous tone support, tightening vein walls that have loosened from hours of sitting.
Horse Chestnut Seed Extract
Cuts down on capillary leakage in your legs. Standardized for aescin content, this seed extract helps reduce the fluid leakage that leaves legs feeling swollen and heavy by evening.
Pine Bark Extract
Opens up the smallest vessels, the ones reaching your fingertips. Rich in procyanidins, this extract supports the microcirculation that larger-vessel formulas tend to ignore.
Bergamot Fruit Extract
Works your cholesterol numbers from a second angle. Standardized for polyphenol content, this citrus extract supports healthy LDL and lipid handling alongside the K2 in this formula.
Taurine
Supports blood pressure without a stimulant in sight. This amino acid helps relax vascular tone, working with magnesium to support numbers already in a healthy range.
Magnesium (as bisglycinate chelate)
The mineral your blood vessels actually need to relax. This gentle, highly absorbable chelate form supports smooth-muscle relaxation in vessel walls, a foundation for the blood pressure support in this formula.
Coenzyme Q10 (ubiquinone)
Fuels steady energy from your cells outward. This mitochondrial nutrient supports even daytime energy without the crash, jitters, or caffeine dependence of a stimulant.
Hesperidin
Pairs with diosmin for capillary strength that holds up. This citrus flavonoid completes the classic venous-support pairing, reinforcing capillary resistance alongside the diosmin in this formula.
PQQ (pyrroloquinoline quinone disodium)
Backs up CoQ10 at the cellular level. This compound supports the mitochondrial machinery behind sustained, stimulant-free energy through the day.
Nattokinase
The clinical-strength dose the category skips. This fermentation-derived enzyme is the fibrin-clearing engine of the formula, delivered enteric-coated so it survives your stomach and reaches your bloodstream intact.
Vitamin K2 (as menaquinone-7)
Steers calcium away from your arteries. This all-trans MK-7 form works alongside the enzyme on your lipid profile while directing calcium toward bone instead of arterial walls.
Rutin
Reinforces the vessel walls carrying that fresh blood flow. This bioflavonoid strengthens capillaries and vein walls so circulation improves without vessels losing structural integrity.
Micronized Diosmin
Targets the heavy, tired feeling in your legs. This micronized flavonoid is dosed for genuine venous tone support, tightening vein walls that have loosened from hours of sitting.
Horse Chestnut Seed Extract
Cuts down on capillary leakage in your legs. Standardized for aescin content, this seed extract helps reduce the fluid leakage that leaves legs feeling swollen and heavy by evening.
Pine Bark Extract
Opens up the smallest vessels, the ones reaching your fingertips. Rich in procyanidins, this extract supports the microcirculation that larger-vessel formulas tend to ignore.
Bergamot Fruit Extract
Works your cholesterol numbers from a second angle. Standardized for polyphenol content, this citrus extract supports healthy LDL and lipid handling alongside the K2 in this formula.
Taurine
Supports blood pressure without a stimulant in sight. This amino acid helps relax vascular tone, working with magnesium to support numbers already in a healthy range.
Magnesium (as bisglycinate chelate)
The mineral your blood vessels actually need to relax. This gentle, highly absorbable chelate form supports smooth-muscle relaxation in vessel walls, a foundation for the blood pressure support in this formula.
Coenzyme Q10 (ubiquinone)
Fuels steady energy from your cells outward. This mitochondrial nutrient supports even daytime energy without the crash, jitters, or caffeine dependence of a stimulant.
Hesperidin
Pairs with diosmin for capillary strength that holds up. This citrus flavonoid completes the classic venous-support pairing, reinforcing capillary resistance alongside the diosmin in this formula.
PQQ (pyrroloquinoline quinone disodium)
Backs up CoQ10 at the cellular level. This compound supports the mitochondrial machinery behind sustained, stimulant-free energy through the day.
What customers are saying about 10, 800FU KINASE
Rated 4.7 / 5 across 12,220 reviews.
5.0Verified Customer
feet dont feel like ice anymore
took about three weeks before i noticed my feet werent freezing all the time. my hands used to go white in the cold and thats happening way less now. wasnt expecting that honestly
Diane R.actually worksworth it
5.0Verified Customer
Heart scan follow up went better
Had a high calcium score come back a while ago and my doctor wanted me watching it closely!! Been on this a couple months and my next scan showed less buildup than expected, capsules are easy to swallow too which is a nice bonus!!
Marcus T.actually works
5.0Verified Customer
the dose and coating sold me
i had tried lower dose nattokinase before and never knew if i was getting enough. after comparing the research, the 10,800 serving and enteric capsules were the two things that made me switch.
Karen L.research grade doseenteric coated
5.0Verified Customer
cholesterol runs in my family so ive been on medication for years but wanted something extra alongside it, my last panel came back lower than it had been in a while, not saying its all this but the timing lines up and my doctor didnt change anything so ill take it.
Patricia W.worth itactually works
5.0Verified Customer
43 bucks for the first bottle stung a little, ngl - box showed up kind of squished but the bottle inside was fine, no damage. Been taking 3 first thing before I start kneading dough and my legs feel less heavy by the afternoon. The refill price made it a bit easier to keep going, and I like reusing the light-blocking sealed bottle that came with it.
Linda G.refill saves moneylighter legs
4.0Verified Customer
Following up after a calcium score scare
My cardiologist flagged some arterial buildup on a scan last year and I started looking into options. I take it with lunch most days since that is when I remember. Bottle does not last quite as long as I would like for the price, but I plan to keep going.
jerry n.worth itpricey
5.0Verified Customer
box showed up fast
readings have been LOWER since i started, box came in good shape too, no dents or anything.
Denise F.actually worksfast shipping
5.0Verified Customer
clot scare, calmer now (doctor was pleased too)
Michelle S.peace of mindtravel friendly
5.0Verified Customer
cholesterol numbers actually moved
started this back in March alongside my statin and by my June bloodwork my LDL had dropped a good bit more than my doctor expected. going on 4 months now and still taking it every day.
Nancy B.cholesterol supportactually works
5.0Verified Customer
I struggle with circulation in my feet and after taking it the first time I felt like a burning feeling around my ankles later in the afternoon. I could instantly tell from that this must be helping with circulation to my feet
Amy T.circulationnoticed when i missed it
5.0Verified Customer
honestly i thought this was going to be another supplement gathering dust in my cabinet but my toes have actually stopped going numb on my morning walks, wich surprised me more than it should have.
Barbara E.circulationdidnt expect this
5.0Verified Customer
legs feel lighter by the end of the day
i sit for long stretches and my feet used to get cold and tingly by late afternoon. a few weeks i feel like they stay warmer, and my legs dont have that same heavy feeling by evening, could be placebo too but i think its working so i'll probably keep taking
Chris V.circulationwarmer feet
1 / 12
Proven Ingredients Featured In:
“A full daily dose of nattokinase slowed arterial plaque buildup and improved cholesterol.”
Reviews in Cardiovascular Medicine
“Pooled clinical trials show nattokinase significantly lowered both systolic and diastolic blood pressure.”
“Vitamin K2 helps keep calcium out of your arteries and in your bones.”
“Menaquinone-7 supports arterial flexibility by curbing calcium buildup in vessel walls.”
“Rutin acts as an antioxidant and is used to support blood-vessel and heart health.”
Feel Warm. Feel Steady.
From colder mornings to long sitting days, here's what makes Natto different.
Warmer Hands & Feet
Lighter, Less Tingly Legs
Support for Healthy Arteries
Steady Energy, No Caffeine
Real Circulation Support. Backed by a Dose That Actually Works.
Most nattokinase bottles give you a token amount; Natto gives you 10,800FU per serving, enteric-coated so it reaches your bloodstream instead of your stomach acid.
Warm Hands & Feet
Circulation you can feel
Artery Support
Keep vessels clear and flexible
Healthy Blood Pressure
Numbers you can feel good about
Steady All-Day Energy
Even energy, no caffeine crash
Warmer Hands & Feet
Artery Support
Healthy Blood Pressure
Clinical-Strength Dose
Cholesterol Support
Steady Energy
Warmer Hands & Feet
Artery Support
Healthy Blood Pressure
Clinical-Strength Dose
Cholesterol Support
Steady Energy
Warmer Hands & Feet
Artery Support
Healthy Blood Pressure
Clinical-Strength Dose
Cholesterol Support
Steady Energy
Your Circulation
Journey with Natto
Natto works with your body in stages, building toward steady, lasting circulation support rather than a one-day fix.
Week 1: Early Shifts
- Hands and feet start to feel warmer
- Legs feel a touch lighter by evening
- You notice circulation on the days you take it
Week 2: Steady Flow
- Less tingling and heaviness in your legs
- Fingers and toes stay warmer, longer
- Energy feels steadier through the afternoon
Week 3: Vessel + Pressure Sync
- Blood pressure trends toward a healthier range
- Arteries feel supported, not just your extremities
- You feel more in control of your numbers
Week 4+: Long-Term Balance
- Warm hands and feet become the norm
- Cholesterol and lipid numbers keep trending right
- Your circulation feels resilient, day after day
5 Reasons Why
5 Reasons Why 10,800FU KINASE Is Different From Everything You've Tried
A real dose. Real delivery. Nothing watered down.
5 Reasons Why 5 Reasons Why 10,800FU KINASE Is Different From Everything You've Tried
A real dose. Real delivery. Nothing watered down.
Reason 1
5x the Nattokinase Most Bottles Sell You
Most nattokinase supplements top out around 2,000 FU a day. This one delivers a full 10,800 FU serving, the level circulation-conscious buyers actually go looking for.
Reason 2
Enteric-Coated So It Actually Survives Your Stomach
An enzyme destroyed by stomach acid never gets the chance to work. These capsules are enteric-coated to reach the intestine intact, which is what makes the dose mean anything at all.
Reason 3
Built for Cold Hands, Feet, and Heavy Legs
Rutin, diosmin, hesperidin, and horse chestnut work on blood flow to cold extremities and tired, heavy legs, support that a bare single-ingredient bottle simply doesn't include.
Reason 4
One Enzyme, Not a Risky Stack
Just one correctly dosed fibrinolytic enzyme, no second clot-dissolving enzyme layered on top to multiply bleeding and bruising risk like some multi-enzyme blends do.
Reason 5
K2, Magnesium, and CoQ10 Doing Real Work Too
180 mcg of K2 helps steer calcium toward bone and away from arteries, magnesium and taurine support blood pressure already in a normal range, and CoQ10 backs steady energy, all dosed at levels you can actually feel, not fairy-dusted trace amounts.
Reason 1
5x the Nattokinase Most Bottles Sell You
Most nattokinase supplements top out around 2,000 FU a day. This one delivers a full 10,800 FU serving, the level circulation-conscious buyers actually go looking for.
Reason 2
Enteric-Coated So It Actually Survives Your Stomach
An enzyme destroyed by stomach acid never gets the chance to work. These capsules are enteric-coated to reach the intestine intact, which is what makes the dose mean anything at all.
Reason 3
Built for Cold Hands, Feet, and Heavy Legs
Rutin, diosmin, hesperidin, and horse chestnut work on blood flow to cold extremities and tired, heavy legs, support that a bare single-ingredient bottle simply doesn't include.
Reason 4
One Enzyme, Not a Risky Stack
Just one correctly dosed fibrinolytic enzyme, no second clot-dissolving enzyme layered on top to multiply bleeding and bruising risk like some multi-enzyme blends do.
Reason 5
K2, Magnesium, and CoQ10 Doing Real Work Too
180 mcg of K2 helps steer calcium toward bone and away from arteries, magnesium and taurine support blood pressure already in a normal range, and CoQ10 backs steady energy, all dosed at levels you can actually feel, not fairy-dusted trace amounts.
30 Day Money-Back Guarantee
Natto vs. Basic single-ingredient nattokinase supplement
Other Brands
10800 FU of nattokinase per daily servingmore than five times the token amount most bottles sell
Around 2,000 FU a day, the low reference amountEnteric-coated vegetarian capsules so the enzyme survives stomach acid and reaches the intestine active
Often uncoated, leaving the enzyme exposed to stomach acid that deactivates it12 clinically framed activesthe enzyme plus K2, rutin, diosmin, hesperidin and more working together
One ingredient in the bottlenattokinase aloneVenotonic flavonoids250 mg rutin, 450 mg diosmin, 50 mg hesperidin and 120 mg horse chestnut — target blood flow to cold extremities and heavy legs
No flavonoid or vein-wall support for cold hands, feet or heavy legs180 mcg vitamin K2 (MK-7) steers calcium toward bone and away from arterial walls, alongside the fibrin-clearing enzyme
Enzyme onlyno K2 to direct calcium away from arteriesNatto vs. Basic single-ingredient nattokinase supplement
30 Day Money-Back Guarantee
30DAYS
FEEL THE DIFFERENCE
30-Day Risk-Free Trial
If you don’t experience warmer hands, warmer feet, and lighter legs within 30 days, Return your bottle within 30 days for a full refund, no questions asked.—No forms to justify, no unopened bottle required..
Peripheral Circulation
Artery Support
Blood Pressure Support
How Does It Work?
The science behind 10,800FU KINASE
A clinical-strength nattokinase dose is delivered intact, then supported by ingredients studied for circulation and vessel health.
Enteric-coated nattokinase: 10,800 FU per serving, protected from stomach acid so it reaches the intestine active.
Vitamin K2 (MK-7): Works alongside the enzyme on lipids while directing calcium toward bone, away from arteries.
Rutin, diosmin & hesperidin: Vessel-wall flavonoids that support blood flow to cold or heavy extremities.
One correctly dosed enzyme, delivered active, working alongside a supporting circulation stack.
About Your Free Gifts
These complimentary extras are included to make your daily routine easier and more enjoyable.
Ceramic Storage Bottle: Opaque glazed ceramic blocks light and the gasket cap seals out air, so the enzyme stays as potent on day thirty as on day one.
The Japanese Circulation Guide: Two hundred pages on what the research and four centuries of Japanese kitchens agree keeps blood moving, from the fermented foods to the daily habits.
What Can 10,800FU KINASE Help With?
Better blood flow to cold hands, feet, and legs
Venotonic flavonoids help support circulation to cold or tingly extremities.
Support artery health
Vitamin K2 helps direct calcium away from arterial walls as you age.
Support healthy blood pressure
Magnesium and taurine support numbers already within a normal range.
One enzyme, correctly dosed
A clinically framed nattokinase serving, without a second fibrinolytic enzyme stacked in.
Support cholesterol & LDL
Bergamot fruit extract works with K2 to support a healthy lipid profile.
More steady energy through the day
CoQ10 and PQQ support even, caffeine-free energy.
When Will I See Results?
Week 1: Early Shifts
- Hands and feet start to feel warmer
- Legs feel a touch lighter by evening
- You notice circulation on the days you take it
Week 2: Steady Flow
- Less tingling and heaviness in your legs
- Fingers and toes stay warmer, longer
- Energy feels steadier through the afternoon
Week 3: Vessel + Pressure Sync
- Blood pressure trends toward a healthier range
- Arteries feel supported, not just your extremities
- You feel more in control of your numbers
Week 4+: Long-Term Balance
- Warm hands and feet become the norm
- Cholesterol and lipid numbers keep trending right
- Your circulation feels resilient, day after day
How Long Until I Get It?
Order now for delivery by September 15 (in United States)
You’ll see the latest location-based arrival estimate again at checkout.
Who Can Use It?
Designed for adults over forty who sit for long stretches, travel often, or simply want a nattokinase dose that reflects the research they've read.
- Adults with cold hands, feet, or heavy legs
- Desk-bound professionals and frequent travelers
- Anyone who researched nattokinase and found shelf doses too low
- People supporting healthy blood pressure or cholesterol already in a normal range
If you are pregnant, nursing, taking blood-thinning medication, or managing a health condition, ask a healthcare professional before use.
Results or Full Refund Guarantee
Your order today is protected by our 30-day money-back guarantee. If you're not completely satisfied for any reason within 30 days, return it for a full refund.*
Rated 4.7 Excellent 12,220 Reviews
10,800FU KINASE
Natto 10,800FU KINASE is a research-grade dose nattokinase supplement designed to help increase circulation in cold hands, feet, and legs, support healthy arteries, and improve overall heart health. No bad natto taste, just three odourless capsules each morning.
93% of customers report: warmer hands and feet within two to four weeks
Peripheral CirculationRutin, diosmin, and horse chestnut target blood flow to cold hands and feet.
Artery SupportVitamin K2 steers calcium toward bone and away from arterial walls.
Blood Pressure SupportMagnesium and taurine support blood pressure already in a normal range.
Cholesterol & LDL SupportBergamot works alongside K2 to support a healthy lipid profile.
Steady EnergyCoQ10 and PQQ support even energy through the day, caffeine-free.
One Enzyme, No Stacking RiskOne correctly dosed fibrinolytic enzyme, never stacked with a second.
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90 capsules / bottle · 3/day · 30-day supply
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If you're not completely satisfied for any reason within 30 days, return it for a full refund.*
What customers are saying
Reviews reflect individual experiences. Individual results may vary. Not intended to diagnose, treat, cure, or prevent any disease.
5.0
Verified CustomerTom H.
cold mornings dont bother me as much
took maybe three weeks before i noticed my feet werent cold all the time anymore, even my hands stopped going numb in the mornings. my legs used to feel heavy by afternoon and thats calmed down too. wasnt expecting it this soon honestly.
5.0
Verified CustomerAngela F.
easy to swallow, actually helps my scan numbers!!
had a calcium score come back high last year and my doctor wasnt thrilled. capsules go down easy, no weird taste, and my next scan is in a few months so fingers crossed!!
5.0
Verified CustomerGREG P.
feet warm up faster now
keep it by the sink and take it after i brush my teeth. after a few weeks my feet stopped staying cold all morning and my legs felt less tingly later in the day.
5.0
Verified CustomerSusan D.
the higher dose made more sense
i had used a lower dose nattokinase before. after reading more about FU per serving, the 10,800 FU dose here was the reason i switched.
5.0
Verified CustomerLogan D.
my ldl runs high in my family so i was just taking a plain nattokinase pill before but switched to this one because it seemed like it did more, still on my statin too but figured a little extra help cant hurt
5.0
Verified CustomerWayne G.
she noticed before i said anything
my wife was surprised i wasnt crashing around 3pm anymore and honestly i hadnt even clocked it myself. i used to get that foggy slump every afternoon and it just kind of stopped happening. now we both take it, recommend it
5.0
Verified CustomerDoug B.
on my third bottle now... my feet used to get so cold at night my wife complained, and my hands would go numb sometimes too from what I think was Raynaud's... that's mostly settled down now and no weird side effects to speak of, so I just keep reordering.
3.0
Verified CustomerGreg R.
still costs more, refill helps
It costs more than the basic pills I used to buy. The discounted refill made the ongoing price more reasonable, and I like reusing the ceramic CycleSeal bottle instead of getting another bulky container each time.
5.0
Verified CustomerKim S.
box showed up dented but pills were fine
Box arrived a little dented on one corner, kind of worried the bottle would be cracked, but everything inside was totally FINE, seal intact and all. I started this for cold feet and tingling around my ankles, and both have been less noticeable after a few weeks.
4.0
Verified CustomerCindy C.
helps but easy to space out on
had some vessel issues my doctor was watching (scary stuff honestly) and this seems to be helping, i just forget a dose sometimes.